Fig. 3

a Dose–response inhibition of HIV-1 replication in U87-CD4-CCR5 cells after 11 days. Each curve displays the mean and SD of 4 independent wells of a representative experiment (n = 3). Viral replication was determined by p24 production in the culture supernatant and expressed as % of the DMSO-treated control. b Toxicity of compound 696 on U87-CD4-CCR5 cells measured by MTT assay after 11 days displayed as percentage live cells (mean and SD of 4 wells) relative to control