Fig. 4

The influence of LBH589 combined with AM1241 on the channels. LBH589 combined with AM1241 activated A endoplasmic reticulum stress pathway (n = 3), B DDR signaling pathway (n = 3) and C and D autophagy (n = 3). Compared with the control group, ^*P < 0.05, ^**P < 0.01, ^***P < 0.001