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Table 4 Extraction recovery evaluation of SAX and 5-OH SAX

From: Pharmacokinetic/Pharmacodynamic modelling of Saxagliptin and its active metabolite, 5-hydroxy Saxagliptin in rats with Type 2 Diabetes Mellitus

Analytes

Norminal

concentration (ng/mL)

Extraction recovery (n = 5) (%)

Mean

SD

RSD

SAX

15

82.58

3.41

4.13

1000

93.37

2.07

2.22

2000

92.96

2.31

2.48

5-OH SAX

3

96.18

3.18

3.30

200

91.86

2.80

3.05

400

89.27

3.90

4.37

VIL

150

92.19

1.91

2.07