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Fig. 5 | BMC Pharmacology and Toxicology

Fig. 5

From: Discovery of Loureirin analogues with colorectal cancer suppressive activity via regulating cell cycle and Fas death receptor

Fig. 5

Compound 4c regulated cell cycle and FAS death receptor. A, volcano plot showing the number of differentially expressed genes between 4c treatment group and the control group. B, heat map showing differentially expressed genes between 4c treatment group and the control group. C, Top 20 up- and down-regulated genes after 4c treatment, including MDM2, CDKN1A and FAS. D, KEGG analysis of the differentially expressed genes after 4c treatment

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