Fig. 2
Effect of luteolin on the proliferation and cell cycle progression of hFOB1.19 cells. (A) The proliferation and cell cycle distribution of luteolin-treated hFOB1.19 cells were detected by using a CCK-8 assay. (B) The cell cycle distribution in each group was detected by using flow cytometry. (C) The proportion of S-phase cells was quantified. LPS induction reduced the proportion of S-phase hFOB1.19 cells after 1, 3, and 5 days, and this reduction was reversed by luteolin. With the combination of LPS and H2O2, the proportion of hFOB1.19 cells in the S phase was significantly reduced after 1, 3, and 5 days. The data are expressed as the means ± SDs (***p < 0.001, **p < 0.01, *p < 0.05)