Fig. 15

Effect of compound 5-a on the relative expression of TNF-α & NF-κB in liver tissue treated with GM. Group A, Normal control; Group; B, GM; Group C, Dexa; Group D, 5-a (10 mg/kg). Each value represents ± S.E.M (n = 5), analysed by using One-way ANOVA (Analysis of variance) using the Duncan test for multiple comparisons. The values having different alphabetical superscriptions in the column significantly different (p ≤ 0.05). Whereas 5-a 2-{5-[(2-hydroxyethyl) sulfanyl]-1,3,4-oxadiazol-2-yl} phenol, GM Gentamicin, Dexa Dexamethasone