Table 2 Effect of the compound 5-a and GM/Dexa on the renal biomarkers

Normal Saline (0.15 ml/kg)

0.93 ± 0.01^c

13.4 ± 0.29^e

141.6 ± 1.208^a

8.78 ± 0.05^a

0.78 ± 0.037^c

8.6 ± 0.70^c

43 ± 0.70^c

GM (100 mg/kg)

3.47 ± 1.55^a

37.76 ± 16.8^a

21.1 ± 9.436^e

4.28 ± 1.91^e

1.28 ± 0.57^a

1.77 ± 0.79^e

8.8 ± 3.97^e

Dexa (10 mg/kg) + GM (100 mg/kg)

1.53 ± 0.15^b

24.74 ± 0.40^b

77.6 ± 0.927^b

7.4 ± 0.07^b

1.04 ± 0.06^b

2.82 ± 0.24^d

14.1 ± 0.24^d

5-a (5 mg/kg) + GM (100 mg/kg)

0.82 ± 0.02^d

22.28 ± 0.36^c

113.2 ± 0.583^c

6.48 ± 0.03^c

0.52 ± 0.03^d

9.36 ± 0.66^b

46.8 ± 0.66^b

5-a (10 mg/kg) + GM (100 mg/kg)

0.83 ± 0.01^c

18.86 ± 0.26^d

121.8 ± 1.157^d

5.52 ± 0.07^d

0.4 ± 0.044^e

46.8 ± 0.6^a

54 ± 0.70^a