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Fig. 3 | BMC Pharmacology and Toxicology

Fig. 3

From: Sodium Houttuyniae attenuates ferroptosis by regulating TRAF6-c-Myc signaling pathways in lipopolysaccharide-induced acute lung injury (ALI)

Fig. 3

SH significantly attenuated LPS-induced ferroptosis in vitro. (A) Observation of mitochondrial structure by transmission electron microscopy in rat ATII cells (scale bar is 500 nm). (B) CCK8 was used for the detection of cell proliferation of rat ATII cells. (C) The cellular iron levels were evaluated by the ferrous iron colorimetric assay kit. (D) Representative ROS fluorescence picture of rat ATII cells. (E) ROS fluorescence intensity. (F-G) Concentrations of GSH and MDA. (H-L) Western blotting was used to detect the expression of FTH1, GPX4, NCOA4, and NOX1 protein. Data are shown as the mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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