Evaluation of the therapeutic potential of novel nanoparticle formulations of glutathione and virgin coconut oil in an experimental model of carbon tetrachloride-induced liver failure

Table 3 Summarizes each group’s liver tissue histopathology lesion scores

Lesion	Congestion of CV	Thrombosis	Hepatic necrosis	Hydrobic degeneration	Mononuclear cell infiltration
Group	Congestion of CV	Thrombosis	Hepatic necrosis	Hydrobic degeneration	Mononuclear cell infiltration
Control	-	-	-	-	-
CCL₄	+++	++	+++	+++	+++
CS	++	++	+++	++	++
Fe₃O₄	++	++	+++	++	++
GSH	+	-	++	++	+
VCO	+	+	++	++	+
Nano-GSH	+	-	+	+
Nano-VCO	+	-	+	+
O	-	-	-	-	-
Nano-O	-	-	-	-	-

- No lesions, + lesions present in 2–3 sections, ++ lesions present in 4–7 sections and +++ lesions present in 8–10 sections
CCL₄ carbon tetrachloride, CS chitosan, GSH glutathione, Fe₃O₄ ferric oxide, O combination of GSH and VCO, VCO virgin coconut oil

ISSN: 2050-6511