Assessing solubility of meloxicam in age-specific gastric and intestinal media relevant to adults and pediatric populations: implications for optimizing dosing in patients for postoperative pain

Table 2 Molecular descriptors of meloxicam

Descriptor	Value
Experimentally determined LogP	0.1
Experimentally determined pKa	4.08
cLogP predicted by ALOGPS	2.28
cLogP predicted by ChemAxon	1.6
pKa (Strongest Acidic) predicted by ChemAxon	4.47
pKa (Strongest Basic) predicted by ChemAxon	0.47
Polar Surface Area predicted by ChemAxon	99.6 Å²
Bioavailability predicted by ChemAxon	100%

ISSN: 2050-6511