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Table 2 Molecular targets of oritavancin from DrugBank

From: In silico molecular targets, docking, dynamics simulation and physiologically based pharmacokinetics modeling of oritavancin

Target name

Uniprot ID

Oritavancin action

General function

Cytochrome P450 3A4

P08684

Inhibitor, Inducer

Vitamin D3 25-hydroxylase activity

Cytochrome P450 2D6

P10635

Inhibitor, Inducer

Steroid hydroxylase activity

Cytochrome P450 2C9

P11712

Inhibitor

Steroid hydroxylase activity

Cytochrome P450 2C19

P33261

Inhibitor

Steroid hydroxylase activity

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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