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Fig. 4 | BMC Pharmacology and Toxicology

Fig. 4

From: Pulrodemstat, a selective inhibitor of KDM1A, suppresses head and neck squamous cell carcinoma growth by triggering apoptosis

Fig. 4

The aberrant upregulation of KDM1A mainly distributed in HNSCC malignant cells. (A) The expression of KDM1A in HNSCC was analyzed by TCGA database. The significance of two sample groups is determined by the Wilcoxon test. (B) The correlation between KDM1A transcripts and HNSCC malignancies were determined by TCGA database. (C) The predictable value of KDM1A in HNSCC was determined by TCGA database via GEPIA online tools. All analytical methods above and R packages were performed using R software version v4.0.3 (The R Foundation for Statistical Computing, 2020). p < 0.05 was considered as statistically significant. (D, E) The expression distribution of KDM1A in HNSCC tumors were determined by single cell RNA-sequencing via TISCH2 database

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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