Fig. 2

Comparative histopathology of trial rodents: (A) Representative (H&E and PAS panel) expressed renal lesions and suggestive impairments; whereas, (immunofluorescent-AGEs and -CML depositions appeared as red) were examined in kidney segments of (i) control; (ii) STZ-induced DN, diabetic nephropathy rats; (iii) DN treated with CD, cinnamaldehyde; and (iv) DN treated with AG, aminoguanidine. Treatment groups were compared with diabetic nephropathy. In the AGEs panel, DAPI was shown as pseudo-green. Schematic plan (left panel). Magnification IHC-AGEs: ×100; H&E and IHC-CML: ×200; PAS: ×400