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Table 2 Top 30 drugs most associated with potential Sarcopenia

From: Drug risks associated with sarcopenia: a real-world and GWAS study

Rank

Medicine classification

ATC

PRR

χ2

1

levofloxacin

J01MA12

9.964255

1057.471

2

pregabalin

N02BF02

7.196023

1023.131

3

atorvastatin

C10AA05

4.680292

903.2603

4

duloxetine

N06AX21

4.765571

527.9015

5

Venlafaxine

N06AX16

5.557867

504.6155

6

quetiapine

N05AH05

4.474581

498.3032

7

simvastatin

C10AA01

5.493394

385.3455

8

Varenicline

N07BA03

4.025715

357.5679

9

gabapentin

N02BF01

5.001612

288.679

10

Alprazolam

N05BA12

4.792169

264.6979

11

zoledronic acid

M05BA08

8.640068

262.688

12

ibandronate

M05BA06

6.615291

232.5815

13

Rosuvastatin

C10AA07

3.107508

221.9797

14

Clonazepam

N03AE01

4.752401

217.6859

15

dalfampridine

N07XX07

7.769447

188.3323

16

risedronate

M05BA07

5.882297

181.6785

17

Celecoxib

M01AH01

3.753647

168.2745

18

ciprofloxacin

J01MA02

6.027133

154.7152

19

Sertraline

N06AB06

3.332583

145.6134

20

Oxycodone

N02AA06

3.018044

140.4555

21

Desvenlafaxine

N06AX23

5.252093

137.2714

22

Codeine and paracetamol

N02AJ06

4.154139

133.4416

23

Peginterferon alfa-2b

L03AB10

5.557315

130.4744

24

diazepam

N05BA01

5.62961

125.3521

25

Parecoxib

M01AH04

5.143158

123.1505

26

Ziprasidone

N05AE04

5.108432

115.3551

27

Paroxetine

N06AB05

3.679182

114.4914

28

Citalopram

N06AB04

4.1355

111.2935

29

Levothyroxine sodium

H03AA01

2.33943

101.3015

30

Zolpidem

N05CF02

3.209565

99.77411