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Table 2 Effect of L-carnitine (LCAR, 300 and 500 mg/kg/day, IP) on serum lipid profile in dexamethasone (DEXA)-toxified rats

From: L-carnitine attenuates autophagic flux, apoptosis, and necroptosis in rats with dexamethasone-induced non-alcoholic steatohepatitis

 

Control

DEXA

DEXA-MET

LCAR500

DEXA-LCAR300

DEXA-LCAR500

Total cholesterol (mg/dL)

101.60 ± 7.55

195.00 ± 31.70*

184.40 ± 41.20*

112.00 ± 19.28

151.20 ± 17.33*

154.00 ± 27.03*

HDL-C (mg/dL)

65.17 ± 5.38

41.71 ± 5.02*

69.50 ± 15.77#

64.00 ± 16.97

65.00 ± 9.21#

68.00 ± 6.93#

Non-HDL-C (mg/dL)

36.33 ± 6.77

152.70 ± 32.71*

115.00 ± 27.60*#

47.50 ± 2.88

86.17 ± 12.53*#

86.00 ± 20.34*#

TGs

(mg/dL)

98.33 ± 19.16

396.50 ± 212.8*

211.00 ± 63.78#

113.80 ± 57.27

200.80 ± 80.24#

161.00 ± 40.58#

  1. Data are shown as means ± SD, n = 6 per group
  2. HDL-C, high-density lipoprotein cholesterol; TGs, triglycerides
  3. *, #P < 0.05 versus control and DEXA groups, respectively