Fig. 16
A The kidney section from the control group shows a renal cortex with normal glomerulus (G) and regular capsular space (U). Narrow proximal convoluted tubules (P) and wider distal convoluted tubules (D) are lined by simple cuboidal epithelium with eosinophilic cytoplasm and central rounded vesicular nuclei. B and C Kidney sections from the control group display normal renal cortex with narrow proximal convoluted tubules (P) and wider distal convoluted tubules (D) lined by simple cuboidal epithelium with eosinophilic cytoplasm and central rounded vesicular nuclei. D The control group kidney section shows a normal renal medulla containing collecting tubules (C) lined by simple cubical epithelium and separated by minimal interstitium (arrows) with peritubular capillaries. E Diseased group kidney section reveals vacuolar degeneration (arrows) in the cytoplasm of convoluted tubules, congestion of peritubular capillaries (stars) within the interstitial space, and some tubular cells appearing shrunken with deeply stained eosinophilic cytoplasm and pyknotic nuclei (angled arrows) [H and E, x400]. F The diseased group kidney section shows congestion and dilatation of peritubular capillaries (stars) within the interstitial space. G The treated group kidney section demonstrates potentially alleviated renal histoarchitecture with normal proximal (P) and distal (D) convoluted tubules and some vacuolated cells lining the renal tubules (arrows). H The treated group kidney section shows potentially alleviated renal histoarchitecture with normal renal glomeruli (G), urinary space (U), normal proximal (P) and distal (D) convoluted tubules, some vacuolated cells lining the renal tubules (arrows), and few shrunken tubular cells with deeply stained pyknotic nuclei (angled arrows). I Treated group kidney section reveals potentially alleviated renal histoarchitecture containing normal proximal (P) and distal (D) convoluted tubules separated by minimal interstitium with slightly congested peritubular capillaries (stars)