Characterization and interactions between piperine and ezetimibe in their Anti-hyperlipidemic efficacy using Biopharmaceutics and Pharmacokinetics

Table 8 Effect of EZ-piperine alone and combination on histopathological changes

Groups	Vacuolization of Hepatocytes	Enlargement Sinusoids	Kupffer-Cell Infiltration	Vascular Congestion
I	-	-	+	-
II	+++	++	+++	+++
III	++	++	+	+
IV	++	++	++	++
V	+	+	-	+
VI	+	+	-	+
VII	-	+	-	-

ISSN: 2050-6511