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Table 2 Top 20 medications associated with suicidal ideation or self-injurious behavior from FAERS ranked by ROR

From: An exploratory study evaluating the 20 medications most commonly associated with suicidal ideation and self-injurious behavior in the FAERS database

Ranking

Drug name

ROR (95%Cl)

PRR (X2)

1

Alprazolam

13.48 (13.01-13.96)

12.86 (35102.65)

2

Zolpidem

13.29 (12.7-13.91)

12.69 (21199.5)

3

Bupropion

11.58 (11.19-11.98)

11.13 (32140.9)

4

Quetiapine

10.66 (10.36-10.96)

10.28 (43123)

5

Fluoxetine

10.63 (10.2-11.08)

10.25 (19644.09)

6

Sertraline

9.43 (9.14-9.74)

9.14 (28183.39)

7

Citalopram

9.35 (9.05-9.67)

9.06 (26552.45)

8

Venlafaxine

8.06 (7.79-8.34)

7.85 (20462.09)

9

Amlodipine

7.66 (7.42-7.91)

7.47 (21384.95)

10

Acetaminophen

7.29 (7.11-7.46)

7.12 (35417.11)

11

Aripiprazole

7.18 (6.96-7.4)

7.01 (21506.44)

12

Duloxetine

7.15 (6.94-7.36)

6.98 (23989.85)

13

Olanzapine

6.09 (5.85-6.35)

5.97 (9565.52)

14

Lamotrigine

5.35 (5.12-5.59)

5.26 (7090.12)

15

Gabapentin

4.89 (4.71-5.08)

4.82 (8270.69)

16

Ibuprofen

3.53 (3.38-3.69)

3.49 (3568.71)

17

Metformin

3.43 (3.29-3.57)

3.4 (3752.76)

18

Sodium oxybate

2.56 (2.45-2.68)

2.55 (1697.59)

19

Oxycodone

2.48 (2.41-2.55)

2.47 (4009.57)

20

Pregabalin

2.03 (1.94-2.12)

2.02 (990.25)