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Table 3 Top 20 medications associated with suicidal ideation ranked by ROR

From: An exploratory study evaluating the 20 medications most commonly associated with suicidal ideation and self-injurious behavior in the FAERS database

Ranking

Drug name

Frequency

ROR (95%Cl)

PRR (X2)

1

Duloxetine

3408

15.98 (15.43-16.55)

15.7 (43685.15)

2

Aripiprazole

1850

9.43 (9-9.89)

9.34 (13266.42)

3

Fluoxetine

711

9.43 (8.75-10.16)

9.33 (5216.6)

4

Sertraline

1298

9.19 (8.7-9.72)

9.1 (9118.85)

5

Venlafaxine

1177

8.15 (7.69-8.64)

8.08 (7134.58)

6

Citalopram

1040

7.64 (7.18-8.13)

7.58 (5817.26)

7

Bupropion

664

6.31 (5.85-6.82)

6.27 (2906.06)

8

Sodium oxybate

1225

5.33 (5.04-5.64)

5.3 (4173.77)

9

Quetiapine

797

4.63 (4.32-4.97)

4.61 (2221.03)

10

Olanzapine

532

4.15 (3.81-4.52)

4.13 (1251.16)

11

Gabapentin

730

3.86 (3.59-4.16)

3.85 (1519.37)

12

Pregabalin

1116

3.6 (3.39-3.82)

3.58 (2034.24)

13

Lamotrigine

454

3.51 (3.2-3.85)

3.5 (803.63)

14

Zolpidem

181

3.5 (3.03-4.06)

3.49 (321.23)

15

Alprazolam

286

3.39 (3.02-3.81)

3.38 (476.91)

16

Oxycodone

1089

1.72 (1.62-1.82)

1.72 (317.92)

17

Acetaminophen

387

1.1 (1-1.22)

1.1 (3.79)

18

Amlodipine

186

1.06 (0.92-1.23)

1.06 (0.69)

19

Ibuprofen

111

0.58 (0.48-0.7)

0.58 (34.06)

20

Metformin

72

0.33 (0.26-0.41)

0.33 (99.09)