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Table 4 Top 20 medications associated with suicide attempt ranked by ROR

From: An exploratory study evaluating the 20 medications most commonly associated with suicidal ideation and self-injurious behavior in the FAERS database

Ranking

Drug name

Frequency

ROR (95%Cl)

PRR (X2)

1

Alprazolam

906

16.92 (15.83-18.08)

16.7 (13002.88)

2

Zolpidem

513

15.47 (14.17-16.88)

15.28 (6742.91)

3

Quetiapine

1634

15.11 (14.38-15.89)

14.94 (20193.14)

4

Aripiprazole

1671

13.18 (12.54-13.85)

13.05 (17639.44)

5

Sertraline

879

9.47 (8.85-10.13)

9.4 (6423.75)

6

Acetaminophen

1918

8.86 (8.46-9.28)

8.81 (12487.49)

7

Fluoxetine

428

8.61 (7.82-9.47)

8.55 (2818.15)

8

Olanzapine

700

8.43 (7.82-9.09)

8.38 (4456.07)

9

Citalopram

745

8.34 (7.75-8.97)

8.29 (4669.17)

10

Amlodipine

897

8.06 (7.54-8.61)

8.01 (5354.2)

11

Venlafaxine

744

7.82 (7.27-8.42)

7.78 (4297.14)

12

Ibuprofen

932

7.65 (7.17-8.17)

7.61 (5199.64)

13

Bupropion

475

6.88 (6.28-7.54)

6.85 (2339.33)

14

Lamotrigine

452

5.36 (4.88-5.88)

5.34 (1571.6)

15

Metformin

749

5.34 (4.96-5.74)

5.32 (2567.74)

16

Duloxetine

669

4.48 (4.15-4.83)

4.46 (1762.02)

17

Sodium oxybate

454

2.97 (2.7-3.26)

2.96 (582.35)

18

Gabapentin

272

2.18 (1.93-2.45)

2.17 (170.93)

19

Oxycodone

872

2.11 (1.97-2.25)

2.1 (492.12)

20

Pregabalin

394

1.91 (1.73-2.11)

1.91 (168.44)