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Table 5 Top 20 medications associated with completed suicide ranked by ROR

From: An exploratory study evaluating the 20 medications most commonly associated with suicidal ideation and self-injurious behavior in the FAERS database

Ranking

Drug name

Frequency

ROR (95%Cl)

PRR (X2)

1

Bupropion

2039

21.94 (20.97-22.95)

21.42 (37960.36)

2

Alprazolam

1569

21.04 (19.99-22.14)

20.56 (28221.59)

3

Zolpidem

956

20.69 (19.39-22.07)

20.22 (17118.98)

4

Amlodipine

2674

17.75 (17.07-18.47)

17.43 (39005.86)

5

Acetaminophen

4365

14.95 (14.49-15.43)

14.73 (50534.46)

6

Quetiapine

1712

11.04 (10.51-11.58)

10.91 (14844.6)

7

Citalopram

1319

10.55 (9.98-11.14)

10.43 (10933.16)

8

Fluoxetine

681

9.73 (9.01-10.5)

9.63 (5192.25)

9

Gabapentin

1464

8.54 (8.1-9)

8.47 (9338.78)

10

Venlafaxine

1059

7.89 (7.42-8.38)

7.82 (6162.56)

11

Lamotrigine

747

6.28 (5.84-6.76)

6.25 (3240.33)

12

Metformin

1167

5.9 (5.57-6.26)

5.87 (4598.07)

13

Sertraline

619

4.63 (4.28-5.01)

4.61 (1728.96)

14

Oxycodone

2468

4.35 (4.17-4.53)

4.33 (5980.7)

15

Olanzapine

450

3.77 (3.44-4.14)

3.76 (904.21)

16

Ibuprofen

651

3.71 (3.43-4.01)

3.7 (1265.06)

17

Duloxetine

434

2.02 (1.84-2.23)

2.02 (222.38)

18

Aripiprazole

329

1.73 (1.56-1.93)

1.73 (101.41)

19

Pregabalin

174

0.59 (0.51-0.68)

0.59 (49.33)

20

Sodium oxybate

35

0.16 (0.11-0.22)

0.16 (155.52)