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Table 5 Adverse events of prednisone and prednisolone in T and R formulations at fast or fed state

From: Food effects and pharmacokinetic evaluation of oral single-dose prednisone acetate and prednisolone in healthy Chinese subjects

Adverse events

Fast

Fed

Severity

T (n = 23)

R (n = 22)

T (n = 23)

R (n = 23)

Alanine aminotransferase increased

2(8.70%)

1(4.55%)

0

0

Mild

Bilirubin increased

0

1(4.55%)

0

0

Mild

Urine white blood cells increased

1(4.35%)

1(4.55%)

0

0

Mild

Urine red blood cells increased

1(4.35%)

0

0

0

Mild

Blood glucose increased

0

1(4.55%)

0

0

Mild

Blood pressure decreased

1(4.35%)

0

0

0

Mild

Electrocardiogram abnormal

0

1(4.55%)

1(4.35%)

1(4.35%)

Mild

Urine latent blood

0

0

1(4.35%)

0

Mild

Dizzy

0

0

0

1(4.35%)

Mild