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Table 3 Basic characteristics of Romiplostim, Eltrombopag, and Avatrombopag case reports

From: Safety analysis of romiplostim, eltrombopag, and avatrombopag post-market approval: a pharmacovigilance study based on the FDA Adverse Event Reporting System

Characteristic

Romiplostim(n = 2,851)

Eltrombopag(n = 10,297)

Avatrombopag(n = 973)

SEX

   

 Female

1235(43.32)

5256(51.04)

513(52.72)

 Male

1001(35.11)

4259(41.36)

385(39.57)

 NA

615(21.57)

782(7.59)

75(7.71)

AEs Reports number

7,311

24,561

2,332

Reporter role

   

 Physician

1277(44.79)

2948(28.63)

248(25.49)

 Other health-professional

586(20.55)

595(5.78)

58(5.96)

 Consumer

443(15.54)

5782(56.15)

384(39.47)

 Pharmacist

538(18.87)

539(5.23)

21(2.16)

 NA

7(0.25)

433(4.21)

262(26.93)

Reporter_country

   

 United States

1756(61.59)

5781(56.14)

917(94.24)

 Japan

245(8.59)

472(4.58)

0(0)

 Europe

178(6.24)

135(1.31)

2(0.21)

 Others

670(23.50)

1148(11.15)

51(5.24)

 NA

2(0.07)

2761(26.81)

3(0.31)

Yearsgroup

   

 < 18

22(0.77)

6(0.04)

2(0.21)

 18–65

53(1.86)

82(0.49)

17(1.74)

 ≥ 65

45(1.58)

118(0.71)

25(2.57)

 NA

2731(95.79)

10,091(98.76)

929(95.48)

Reported year

   

 2018–2023

2851

10,297

973