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Table 3 Safety-related adverse drug events among different ADCs

From: Gastrointestinal toxicity of antibody–drug conjugates: a pharmacovigilance study using the FAERS database

Drug names

ADC-associated

gastrointestinal AEs as PSn (%)

ROR (95%CI)

PRR (95%CI)

χ2

BV

137

5.79(4.86; 6.90)

5.61(4.73; 6.64)

486.06

EV

209

3.26(2.82; 3.75)

3.02(2.66; 3.43)

295.56

GO

22

7.87(5.13; 12.07)

7.54(5.01; 11.34)

119.03

IO

30

11.12(7.71; 16.03)

10.68(7.53; 15.16)

254.45

MS

54

4.37(3.28; 5.80)

3.80(3.00; 4.81)

120.00

PV

80

6.47(5.16; 8.10)

6.20(5.00; 7.67)

345.72

SG

183

5.19(4.44; 6.06)

4.61(4.03; 5.267)

528.25

TD

764

4.22(3.91; 4.54)

3.63(3.42; 3.86)

1685.08

TE

38

3.93(3.12; 4.95)

3.85(3.08; 4.83)

154.49