Table 1 Study cohort characteristics according to past Metformin usage
Variable | All patients [n = 54,869] | non-Metformin [n = 34,551] | Metformin [n = 20,318] | P-value |
|---|---|---|---|---|
Male gender; N (%) | 32,747 (59.7) | 21,061 (61) | 11,686 (57.5) | < 0.001 |
Age*; years (median [IQR]) | 71 [62, 79] | 71 [62, 79] | 70 [62, 78] | < 0.001 |
MDS; N (%) | 287 (0.5) | 154 (0.4) | 133 (0.7) | 0.001 |
CHF; N (%) | 9,837 (17.9) | 6,338 (18.3) | 3,499 (17.2) | 0.001 |
CKD; N (%) | 3,428 (6.2) | 3,074 (8.9) | 354 (1.7) | < 0.001 |
Dementia; N (%) | 2,114 (3.9) | 1,496 (4.3) | 618 (3) | < 0.001 |
Hypertension; N (%) | 33,162 (60.4) | 21,260 (61.5) | 11,902 (58.6) | < 0.001 |