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Table 3 The laboratory values and comparisons of the oxidant and antioxidant parameters

From: Oxidative stress and anti-oxidant status in children with sepsis

 

Sepsis group

Control group

P values

TAS (mmol Trolox equiv./L)

4.28 ± 0.66

6.56 ± 0.89

0.032

TOS (µmol H2O2 equiv./L)

51.33 ± 12.46

37.30 ± 9.24

0.019

OSI (arbitrary unit)

0.12 ± 0.05

0.06 ± 0.02

0.023

PON1 (U/L)

10.21 ± 5.17

21.75 ± 10.11

0.042

Plasma 8-OHdG levels (ng/ml)

4.03 ± 1.49

1.56 ± 1.51

0.039

Native thiol (mmol/L)

492.72 ± 56.39

388.41 ± 43.57

0.022

Disulphide (mmol/L)

11.99 ± 5.43

13.48 ± 7.01

0.041

Total thiol (mmol/L)

516.71 ± 53.90

415.37 ± 46.13

0.035

Disulphide/native thiol percent ratio (%)

2.43 ± 1.28

3.47 ± 1.76

0.011

Disulphide/total thiol percent ratio (%)

2.32 ± 1.13

3.24 ± 1.37

0.015

Native thiol/total thiol percent ratio (%)

95.35 ± 6.40

93.50 ± 5.88

0.017

  1. *TAS: Total Antioxidant Status, TOS: Total Oxidant Status, OSI: Oxidative Stress Index, PON1: Paraoxonase 1 Activity Measurement
  2. * Data are presented with mean values ± standard deviation (SD)