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Fig. 3 | BMC Pharmacology and Toxicology

Fig. 3

From: Dapagliflozin attenuates metabolic dysfunction-associated steatotic liver disease by inhibiting lipid accumulation, inflammation and liver fibrosis

Fig. 3

DaPa suppresses oxidative stress in DIO mice. (A) Representative liver images stained with Oil Red O. (scale bar, 100 μm). (B) TG and TC levels in the CON, DIO, and DIO + DaPa groups. (C) MDA and GSH levels in liver tissues. (D) Histogram of relative fluorescence intensity of ROS in liver tissues. (E) mRNA levels of ATF4, CHOP, and XBP1 in CON, DIO, and DIO + DaPa groups. Data are presented as mean ± SD (n = 6). *p < 0.05, **p < 0.01, and ***p < 0.001, *comparison between the CON and DIO groups; #p < 0.05, ##p < 0.01, ###p < 0.001, #comparison between the DaPa-treated and DIO groups

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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