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Table 3 Biochemical parameters in different experimental groups (n = 10)

From: Therapeutic role of melatonin on acrylamide-induced neurotoxicity via reducing ER stress, inflammation, and apoptosis in a rat model

Parameters

Experimental groups

Control

ACR

MEL10+ACR

MEL20+ACR

MEL20

MDA (nmol/mg)

3.49 ± 0.41a

5.87 ± 0.63b

4.97 ± 0.39b

4.12 ± 0.21c

3,89 ± 0,39ac

SOD (U/mg)

7.11 ± 0.21a

6.08 ± 0.23b

6.50 ± 0.14c

6.90 ± 0.11a

6.90 ± 0.19 a

GSH (µmol/g)

0.445 ± 0.031a

0.314 ± 0.025b

0.376 ± 0.015c

0.423 ± 0.020a

0.436 ± 0.029a

GPx (U/mg)

12.30 ± 0.38a

8.30 ± 0.79b

9.45 ± 0.87b

11.30 ± 0.56c

11.91 ± 0.48ac

CAT (U/mg)

20.73 ± 1.02a

15.05 ± 0.43b

16.68 ± 1.16b

19.72 ± 1.23a

20.58 ± 0.98a

TNF-α (ng/L)

73.56 ± 2.46a

90.54 ± 3.44b

84.57 ± 1.99c

76.01 ± 2.33a

74.43 ± 1.45a

IL-1β (pg/L)

405.31 ± 21.20a

491.15 ± 22.96b

448.48 ± 19.43c

415.44 ± 17.24ac

409.91 ± 16.11a

IL-6 (pg/ml)

34.76 ± 1.90a

46.84 ± 2.88b

43.35 ± 1.96b

37.69 ± 2.40a

36.26 ± 2.31a

nNOS (ng/ml)

8.80 ± 0.73a

14.10 ± 1.06b

10.79 ± 1.33c

9.45 ± 0.66ac

9.29 ± 0.64ac

AChE (ng/ml)

7.68 ± 0.78a

10.30 ± 0.64b

8.68 ± 1.00a

7.95 ± 0.75a

7.76 ± 0.83a

MAO (nmol/min/mg)

1.85 ± 0.13a

3.03 ± 0.30bc

2.44 ± 0.31c

2.07 ± 0.24ac

2.01 ± 0.24ac

  1. Statistical significance between groups within each row is denoted by different letters (a, b, c). Values are reported as mean ± SEM (Standard Error of the Mean). Groups marked with different letters show significant differences (a-b: p < 0.01; a-c: p < 0.05, n = 10)