Table 1 The specific formulas and positive criteria of the four algorithms

ROR

ROR = ad/bc

Lower limit of 95% CI > 1, N ≥ 3

95%CI = eln^{(ROR)±1.96(1/a+1/b+1/c+1/d)0.5}

PRR

PRR = [a(c + d)]/[c(a + b)]

PRR ≥ 2, χ² ≥ 4, N ≥ 3

χ² = [(ad–bc)²](a + b + c + d)/[(a + b)(c + d)(a + c)(b + d)]

BCPNN

IC = log₂a(a + b + c + d)/[(a + c)(a + b)]

IC025 > 0

95%CI = E(IC) ± 2[V(IC)]^0.5

MGPS

EBGM = a(a + b + c + d)/[(a + c)(a + b)]

EBGM05 > 2

95%CI = eln^{(EBGM)±1.96(1/a+1/b+1/c+1/d)0.5}