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Fig. 6 | BMC Pharmacology and Toxicology

Fig. 6

From: Can vildagliptin protect against radiation-induced premature ovarian failure? Insights into the AMPK and AKT signaling pathways

Fig. 6

Immunohistochemical detection of Nrf2 expression (x 400). (A, B) Control and vilda alone groups showed minimal immunostaining, respectively. (C) Ovaries from irradiated rats showed extensive brown immunostaining (increased cytoplasmic Nrf2). (D) Vilda co-administration resulted in a marked reduction in cytoplasmic Nrf2. (E) Quantitative image analysis for Nrf2 immunostaining was expressed as optical density (O.D.). (F) Scoring of the immunostaining considering both the staining intensity and the percentage of positive cells

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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