Fig. 1

linc01278 expression and cell proliferation and apoptosis in HR and Sev pretreated cardiomyocytes. (A) RT-qPCR observation of linc01278 mRNA expression in human cardiomyocytes AC16 from control, HR, Ser, si-NC, and si-linc01278 groups. (B) Cell cultures of control, HR, Ser, si-NC, and si-linc01278 groups were monitored at 0 h, 24 h, 48 h, and 72 h OD values at 450 nm. (C) Flow cytometry to observe the number of apoptosis in cardiomyocytes of control, HR, Ser, si-NC, and si-linc01278 groups. D-E RT-qPCR to detect the apoptosis-related protein genes Bax, and Bcl − 2 mRNA expression. F: Western blot plot of apoptosis-related protein (Bax, Bcl-2) expression after different treatments. * P<0.05, ** P<0.01, *** P<0.001, **** P<0.0001