Fig. 4

Effect of Sev pretreatment on the proliferation and apoptosis ability of linc0278/miR-134-5p regulated HR cardiomyocytes. (A) Changes in miR-134-5p mRNA expression were detected by RT-qPCR. (B) Effect of Sev pretreatment on the proliferative capacity of HR cardiomyocytes (OD = 450 nm). (C) Changes in the amount of apoptosis in Sev-pretreated HR cardiomyocytes observed by flow cytometry. D-E RT-qPCR to detect changes in the expression of apoptosis-related protein genes Bax and Bcl-2 mRNA in Sev-pretreated HR cardiomyocytes. F: Effect of Sev pretreatment on the expression of apoptosis-related proteins after transfection. * P<0.05, ** P<0.01, *** P<0.001, **** P<0.0001