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Fig. 5 | BMC Pharmacology and Toxicology

Fig. 5

From: Sevoflurane reduces cardiomyocyte injury in a hypoxia/reoxygenation model of cardiomyocytes through the linc01278/miR-134-5pt regulatory axis

Fig. 5

Effects of Sev preconditioning on linc0278/miR-134-5p-regulated HR myocyte injury and oxidative stress levels. A-C Expression of cardiomyocyte injury markers cTnI, CK-MB, and LDH in Sev-preconditioned HR myocytes under normal conditions, after silencing of linc01278, and after concomitant use of miR-134-5p inhibitor. (A) cTnl. (B) CK-MB. (C) LDH. D-F The levels of oxidative stress markers MDA, SOD and GSH-Px in cardiomyocytes co-regulated by miR-134-5p and linc01278 were measured in Sev-treated H/R cells. (D) MDA. (E) SOD. (F) GSH-Px. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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