Table 1 Demographic and clinical characteristics of melasma - related reports collected from the FAERS database between January 2004 and June 2024
Characteristics | Case number | Case proportion |
|---|---|---|
Number of events | 408 | |
Sex | ||
F | 346 | 84.8% |
M | 35 | 8.6% |
Missing | 27 | 6.6% |
Weight(kg) | ||
<50 | 12 | 2.9% |
>100 | 7 | 1.7% |
50~100 | 123 | 30.1% |
Missing | 266 | 65.2% |
Age(year) | ||
18–35 | 96 | 23.5% |
36–50 | 92 | 22.5% |
51–65 | 26 | 6.4% |
66–85 | 26 | 6.4% |
Missing | 168 | 41.2% |
Reported Person | ||
Consumer | 216 | 52.9% |
Health Professional | 18 | 4.4% |
Lawyer | 4 | 1.0% |
Physician | 78 | 19.1% |
Other health-professional | 41 | 10.0% |
Pharmacist | 12 | 2.9% |
Missing | 39 | 9.6% |
Reported Countries (top five) | ||
United States | 234 | 57.4% |
United Kiongdom | 23 | 5.6% |
France | 19 | 4.7% |
Brazil | 14 | 3.4% |
Italy | 9 | 2.2% |
Outcome | ||
Death | 2 | 0.5% |
Life-Threatening | 4 | 1.0% |
Hospitalization | 41 | 10.0% |
Disability | 15 | 3.7% |
Other Serious | 116 | 28.4% |
Missing | 227 | 55.6% |
Indications (top five) | ||
Contraception | 110 | 27.0% |
Acne | 8 | 2.0% |
Breast cancer | 8 | 2.0% |
Multiple sclerosis | 8 | 2.0% |
Rheumatoid arthritis | 7 | 1.7% |