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Table 6 Follow up the sCr in both groups

From: Trimetazidine effect on kidney function in patients undergoing coronary procedures

CIN

Group I

(No.=205)

Group II

(No.=205)

Test

P-value

Unadjusted

P- Value

Bonferroni

P -Value

FDR

After three days

27(13.2%)

45(22.0%)

Chi-Squared

0.019*

0.352

0.047*

Applying the same cut points of the CIN definition

after one month (extended follow-up)

13(6.3%)

27(13.2%)

Chi-Squared

0.020*

0.060

0.050*

Mc Nemar test from three days to one month(extended follow-up with the same limits of CIN definition)

Of 27 cases at three days, 21 (77.8%) patients became free from CIN, and 6 (22.2%) cases with consistent CIN.

Seven new cases developed CIN in one month.

Out of 45 cases at three days, 27 (60%) patients became free from CIN, and 18 (40%) cases with consistent CIN.

Nine new cases developed CIN in one month

Mc Nemar

< 0.001*

< 0.001*

< 0.001*

  1. CIN: Contrast-induced Induced Nephropathy, sCr: Serum Creatinine
  2. *Bonferroni-adjusted α = 0.002; FDR-adjusted p-values calculated using the Benjamini-Hochberg method. Chi-squared p-values (0.019, 0.020) not significant at Bonferroni α = 0.002 but borderline significant with FDR