Table 1 Basic information of voxelotor ADE reports
Characteristics | Case Number, n | Case proportion, n% | |
|---|---|---|---|
Gender | Female | 12,378 | 59.22 |
Male | 8149 | 38.99 | |
Not Specified | 375 | 1.79 | |
Age(year) | < 18 | 2932 | 14.03 |
18–44 | 7233 | 34.60 | |
45–64 | 3011 | 14.41 | |
> 64 | 413 | 1.98 | |
Unknow | 7313 | 34.99 | |
Indications (TOP five) | Sickle cell disease | 13,423 | 64.22 |
Product used for unknown indication | 4673 | 22.36 | |
Sickle cell anaemia with crisis | 1117 | 5.34 | |
Not Specified | 709 | 3.39 | |
Sickle cell anaemia | 294 | 1.41 | |
Serious outcome | Death | 309 | 1.48 |
Hospitalization | 7191 | 34.40 | |
Life-Threatening | 31 | 0.15 | |
Disability | 9 | 0.04 | |
Other Serious Outcome | 1822 | 8.72 | |
Reported countries (top five) | United States | 20,263 | 96.94 |
Not Specified | 437 | 2.09 | |
France | 111 | 0.53 | |
Germany | 37 | 0.18 | |
United Kiongdom | 32 | 0.15 | |
Reporting year | 2024 | 629 | 3.01 |
2023 | 4570 | 21.86 | |
2022 | 9576 | 45.81 | |
2021 | 3487 | 16.68 | |
2020 | 2639 | 12.63 | |
2019 | 1 | 0.00 | |
Reported Person | Consumer | 18,606 | 89.02 |
Health profession | 2257 | 10.8 | |
Lawyer | 2 | 0.01 | |
Unknow | 37 | 0.18 | |