Table 3 It presents the absorbance values and corresponding drug release percentages at different time intervals. The results confirm that modified diatoms release diclofenac more gradually than unmodified diatoms, demonstrating their potential for sustained ocular drug delivery
Time (hours) | Absorbance (Unmodified) | Drug Release (%) (Unmodified) | Absorbance (Modified) | Drug Release (%) (Modified) |
|---|---|---|---|---|
0 | 0.000 | 0.0 | 0.000 | 0.0 |
0.5 | 0.250 | 15.2 | 0.180 | 9.5 |
1 | 0.420 | 28.7 | 0.310 | 17.3 |
2 | 0.680 | 45.8 | 0.500 | 27.6 |
4 | 0.890 | 62.1 | 0.730 | 41.8 |
6 | 1.020 | 78.3 | 0.890 | 56.2 |
8 | 1.150 | 92.4 | 1.010 | 68.5 |