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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: Quercetin-mediated restoration of high-fat diet-induced male reproductive dysfunction through modifying spermatogenesis and unraveling 3β-HSD, 17β-HSD, and StAR pathways

Fig. 2

Testicular histopathological alterations in response to QRT and HFD in rats. Photomicrographs of the testes stained with H&E illustrate distinct histological changes in different experimental groups. In Fig. 2A, the testes from control and QRT-administered rats, showcasing normal seminiferous tubules and spermatogenic cell layers (black arrowhead), as well as free sperm within the tubule lumen (white arrowhead). In Fig. 2B, testes from HFD-fed rats reveal marked degenerative changes within the spermatogenic cells (black arrowheads), along with severe interstitial edema (white arrowhead). Figure 2C present testes from QRT + HFD-fed rats, demonstrating a significant reduction in degenerative changes within the spermatogenic cells (black arrowheads) in addition to an increase in sperm presence within the lumen (white arrowhead) (Fig. 2C1), and a decrease in interstitial edema (Fig. 2C2). All images are captured at a magnification of X200, with a scale bar indicating 50 μm

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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