Characteristics | Total(N) | HR(95% CI) Univariate analysis | P value Univariate analysis | HR(95% CI) Multivariate analysis | P value Multivariate analysis |
---|---|---|---|---|---|
TOP2A | 698 | ||||
Low | 349 | Reference | Reference | ||
High | 349 | 4.080 (3.076–5.411) | < 0.001 | 1.970 (1.041–3.730) | 0.037 |
SMO | 698 | ||||
Low | 348 | Reference | Reference | ||
High | 350 | 3.412 (2.614–4.454) | < 0.001 | 1.582 (1.113–2.247) | 0.010 |
CASP6 | 698 | ||||
Low | 348 | Reference | Reference | ||
High | 350 | 5.963 (4.459–7.975) | < 0.001 | 1.713 (1.043–2.813) | 0.034 |
PSMB9 | 698 | ||||
Low | 348 | Reference | Reference | ||
High | 350 | 4.487 (3.416–5.895) | < 0.001 | 1.678 (1.161–2.426) | 0.006 |
GRIN1 | 698 | ||||
Low | 349 | Reference | Reference | ||
High | 349 | 0.362 (0.280–0.468) | < 0.001 | 0.619 (0.398–0.963) | 0.034 |
MCL1 | 698 | ||||
Low | 348 | Reference | Reference | ||
High | 350 | 1.871 (1.465–2.388) | < 0.001 | 1.467 (1.070–2.012) | 0.017 |
BCHE | 698 | ||||
Low | 349 | Reference | Reference | ||
High | 349 | 0.588 (0.462–0.750) | < 0.001 | 0.716 (0.532–0.964) | 0.028 |
CA12 | 698 | ||||
Low | 348 | Reference | Reference | ||
High | 350 | 2.586 (2.013–3.323) | < 0.001 | 1.821 (1.350–2.456) | < 0.001 |
NTRK3 | 698 | ||||
Low | 349 | Reference | Reference | ||
High | 349 | 0.383 (0.295–0.496) | < 0.001 | 0.651 (0.474–0.895) | 0.008 |
AURKB | 698 | ||||
Low | 349 | Reference | Reference | ||
High | 349 | 4.446 (3.355–5.891) | < 0.001 | 1.766 (1.022–3.053) | 0.042 |
CA3 | 698 | ||||
Low | 347 | Reference | Reference | ||
High | 351 | 5.008 (3.791–6.615) | < 0.001 | 1.521 (1.044–2.214) | 0.029 |
PTGS1 | 698 | ||||
Low | 348 | Reference | Reference | ||
High | 350 | 2.998 (2.309–3.891) | < 0.001 | 1.704 (1.085–2.678) | 0.021 |
ADORA1 | 698 | ||||
Low | 348 | Reference | Reference | ||
High | 350 | 2.127 (1.665–2.717) | < 0.001 | 1.387 (1.021–1.884) | 0.037 |
MGMT | 698 | ||||
Low | 348 | Reference | Reference | ||
High | 350 | 1.775 (1.392–2.264) | < 0.001 | 1.522 (1.158–2.000) | 0.003 |
NFE2L2 | 698 | ||||
Low | 349 | Reference | Reference | ||
High | 349 | 2.247 (1.748–2.890) | < 0.001 | 2.153 (1.532–3.027) | < 0.001 |
AVPR1B | 698 | ||||
Low | 349 | Reference | Reference | ||
High | 349 | 1.273 (1.002–1.617) | 0.048 | 1.471 (1.133–1.909) | 0.004 |