Fig. 3

Signal detection at the PT level. The figure highlights all 25 positive PTs that meet the criteria of all four algorithms and have a report count of no less than 10. The left panel sequentially displays the SOC name, PT name, and signal strength generated by the different algorithms. On the right, the forest plot illustrates the log2-transformed ROR values along with their 95% confidence intervals. Asterisks indicate unexpected signals not listed in the drug label. SOC, system organ class; PT, preferred term