Table 3 The pooled prevalence of different types of potential drug‒drug interactions (pDDIs) among elderly patients in Africa
From: Drug-drug interaction among elderly patients in Africa: a systematic review and meta-analysis
Types of DDIs | Number of study | Prevalence (95% CI) | Heterogeneity | |
|---|---|---|---|---|
I2 (%) | p- value | |||
Major DDIs | 7 | 20.59 (6.42, 34.79) | 99.1 | 0.000 |
Moderate DDIs | 8 | 69.40 (56.15, 82.65) | 98.8 | 0.000 |
Minor DDIs | 7 | 34.32% (8.44, 60.19) | 99.6 | 0.000 |
Contra indicated DDIs | 2 | 1.59 (-1.56, 4.75) | 76.1 | 0.041 |
PK DDIs | 2 | 22.57 (18.57, 26.58) | 0.0 | 0.594 |
PD DDIs | 2 | 73.14 (68.89, 77.39) | 0.0 | 0.975 |
Mixed (PK& PD) DDIs | 2 | 4.07 (1.91, 6.23) | 19.4 | 0.265 |