Fig. 4
From: Protective effects of Alamandine against doxorubicin-induced liver injury in rats

Histopathologic sections of the liver in different experimental groups (H&E stain, ×100 and ×400). Control (I) and Alamandine (IV) groups show normal hepatic structure. DOX-treated group (III) displays hepatocyte ballooning and necrosis (thin arrows). Co-treatment with alamandine (V) shows mild hydropic degeneration (thick arrows), indicating hepatoprotection. Thick black arrows: hydropic degeneration of hepatocytes; Thin arrows: cell necrosis