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Table 1 Effects of DOX, Almandine, or both on liver enzyme levels in male rats

From: Protective effects of Alamandine against doxorubicin-induced liver injury in rats

Groups

Control

(Group I)

Sham

(Group II)

DOX

(Group III)

Alamandine

(Group IV)

Alamandine + DOX

(Group V)

ALT (SGPT), U/L

79.87 ± 7.73

85.70 ± 8.10

286 ± 68.79*

84.27 ± 35.40

109.14 ± 12.17**

AST (SGOT), U/L

110.14 ± 5.40

113.11 ± 5.32

235.12 ± 21.32*

108.28 ± 4.60

137.36 ± 6.72**

ALP, U/L

203 ± 2.78

183 ± 5.85

290 ± 5.61*

189 ± 5.32

198.6 ± 8.25**

  1. Values are expressed as mean ± SD (n = 7 per group). *p < 0.05 vs. Control group (Group I); **p < 0.05 vs. DOX group (Group III)
  2. Abbreviations: ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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