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Table 2 Effects of DOX, Alamandine, or their combination on liver oxidative stress markers in rats

From: Protective effects of Alamandine against doxorubicin-induced liver injury in rats

Groups

Control

(Group I)

Sham

(Group II)

DOX

(Group III)

Alamandine

(Group IV)

Alamandine + DOX

(Group V)

SOD (U/mg protein)

65.7 ± 3.44

63.9 ± 3.97

32.2 ± 6.22*

68.27 ± 3.65

52.04 ± 9.52**

MDA (nmol/mg protein)

6.20 ± 1.85

6.4 ± 2.67

11.06 ± 0.03*

6.7 ± 2.1

8.2 ± 0.012**

CAT (U/mg protein)

62 ± 5.82

65 ± 4.50

93.32 ± 34.61*

59 ± 6.61

72.34 ± 8.31**

  1. Data are expressed as mean ± SD (n = 7 per group). *p < 0.05 vs. Control group (Group I); **p < 0.05 vs. DOX group (Group III)
  2. Abbreviations: SOD: superoxide dismutase; MDA: malondialdehyde; CAT: catalase
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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