Table 5 The viscosity, gelation temperature, gelation time, and desirability of formulations B1– B9, and Bpred
From: In-situ gel bases ocular delivery system of Ganciclovir, in-vivo and in-vitro investigation
Formulation code | Concentration of poloxamer 407 (%w/v) | Concentration of HPMC E-50 LV (%w/v) | Viscosity (cPs) | Gelation temperature (°C) | Gelation time (Seconds) | Desirability |
|---|---|---|---|---|---|---|
B1 | 5 | 1 | 6.78 | 45.29 | 598 | 0.095 |
B2 | 10 | 0.75 | 16.93 | 41.02 | 422 | 0.420 |
B3 | 5 | 0.75 | 4.45 | 45.34 | 618 | 0.045 |
B4 | 15 | 0.5 | 60.98 | 39.15 | 191 | 0.953 |
B5 | 15 | 1 | 64.81 | 39.03 | 183 | 0.992 |
B6 | 15 | 0.75 | 61.7 | 39.46 | 189 | 0.976 |
B7 | 10 | 1 | 22.34 | 40.76 | 428 | 0.465 |
B8 | 10 | 0.5 | 10.87 | 41.45 | 432 | 0.374 |
B9 | 5 | 0.5 | 2.33 | 46.23 | 630 | 0 |
Bpred | 15 | 0.992 | 65.62 | 39.14 | 187 | 0.992 |