Skip to main content

Table 7 The diagnostic accuracy, sensitivity, specificity, and accuracy rate of predictors of outcome of creatinine day1 and 2, Cystatin C and proteinuria (ACR) in early assessment of acute renal toxicity

From: Predictive role of cystatin C and increased proteinuria in early assessment of acute renal toxicity in patient poisoned by nephrotoxic drugs and poisons

 

Cut-off

AUC

Sensitivity

Specificity

PPV

NPV

P value

Creatinine 1

mg/dl

> 2.5

0.327

5.1%

95%

66.7%

20.2%

0.017

Creatinine2

mg/dl

> 2.3

0.873

79.7%

85%

95.5%

53%

< 0.001*

Cystatin C (mg/l)

> 1.1

0.993

97.47

100

100

91.3

< 0.001*

Proteinuria (ACR)

> 28

0.805

65.82

100

100

43.7

< 0.001*

  1. ACR: albumin creatinine ratio, AUC: area under the curve, PPV: positive predictive value, NPV: negative predictive value, *: significant as P value ≤ 0.05
Back to article page

BMC Pharmacology and Toxicology

ISSN: 2050-6511

Contact us