Table 2 The experimental conditions for the optimization of pH-responsive in-situ gel
Variables | Level of variables | ||||
|---|---|---|---|---|---|
Independent | -α | -1 | 0 | + 1 | +α |
X1 = Concentration of Carbopol 934 (%w/w) | 0.15 | 0.2 | 0.3 | 0.4 | 0.44 |
X2 = Concentration of Chitosan (%w/w) | 0.21 | 0.3 | 0.5 | 0.7 | 0.78 |
Response | Dependent | ||||
Y1 = Gelation pH | 5.7- 7 | ||||
Y2 = Gelation time | 0.9–3 min | ||||
Y3 = viscosity | 1007–2200 Pa.s | ||||