From: Optimization and preparation of in-situ mucoadhesive gel of azithromycin hydroxypropyl-β-cyclodextrin inclusion complex against upper respiratory tract infections
Formulations
Staphylococcus aureus zone of inhibition (Mean ± SD, n = 3) and MIC
12 h
24 h
48 h
MIC
Azithromycin
11 ± 1.31 mm
15 ± 1.12 mm
19 ± 1.27 mm
3 µg/mL
In-situ gel
18 ± 2.16 mm
28 ± 2.05 mm
31 ± 3.54 mm
1 µg/mL