Comparative study on drug encapsulation and release kinetics in extracellular vesicles loaded with snake venom L - amino acid oxidase

Table 7 Table depicting the best fit kinetic models for release study

Group	Zero-order model (Q_t = Q₀ + K₀t)	First order model (ln Q_t = lnQ₀ + K₁t)	Higuchi model (Qt = K_H x t^1/2)	Korsmeyer-Peppas model (Q_t/Q_∞ = K_ktⁿ)
Pure drug	R² = 0.946	R² = 0.457	R² = 0.76	R² = 0.946
Co-incubation	R² = 0.916	R² = 0.688	R² = 0.75	R² = 0.71
Freeze thaw	R² = 0.980	R² = 0.58	R² = 0.84	R² = 0.992

ISSN: 2050-6511