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Table 3 Linearity results from a series of concentrations of Fosamprenavir and its impurities

From: A new RP-HPLC approach for estimation of potential impurities of Fosamprenavir - method development and validation

Concentration

(ppm)

Peak area (m AU)

 

Amino

Propyl

Isomer

Fosamprenavir

Nitro

Amprenavir

0.5

10,240

10,041

16,685

6900

3719

19,056

0.75

15,634

15,579

25,589

10,046

6015

31,261

1

21,484

21,038

34,669

13,936

8218

41,900

1.25

27,145

26,887

43,588

17,240

10,295

53,117

1.5

32,874

32,133

52,146

20,709

12,317

63,370

R2

0.999

0.999

0.999

0.999

0.999

0.999

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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